The SpinChem® rotating bed reactor (RBR) maximizes the convective mass transfer to the solid phase by generating a circulating flow. As the RBR spins, solution is repeatedly passed through the packed bed inside the RBR by centrifugal force. As every liquid parcel makes multiple passages through the RBR, the reaction rates are increased, and the solid phase utilization maximized.
Boosted reaction rates
Real-time video comparing neutralization speed between a SpinChem® RBR and a stirred tank reactor (STR). The video reveals the gentle and efficient mass transfer conducted by the RBR. The results were a 30% faster ion-exchange neutralization of the base, as well as a completely clear solution without any particles.
Remarkable mass transfer
Video showing the efficient phase-transfer between emulsified immiscible liquids and an ion exchange resin when using a SpinChem® RBR. Fine emulsion droplets were created, resulting in effective phase-transfer between the two liquids and the solid phase.
Prolonged solid phase lifespan
When using a SpinChem® RBR, the solid phase is protected within the rotating cylinder. This means that even fragile materials, such as molecular sieves, polymer beads and alginate particles are protected from grinding. The picture shows levels of grinding of molecular sieves using a stirred tank reactor and an RBR, respectively.
No filtration steps
With the resin retained inside the SpinChem® RBR, there are no solid phase particles or solid phase debris suspended freely in the solution. This means that when using the RBR, filtration steps are completely cut out from the workflow. Furthermore, washing, storing and exchanging the solid phase particles are made very quick and simple.
Maintained enzyme activity
Immobilized enzyme activity is preserved through consecutive batches when using the SpinChem® RBR. When comparing the enzyme activity between reactions using an RBR and a conventional STR, the RBR contributes to maintaining significantly higher activity over multiple runs. Data on next slide from biocatalyzed amidation.