Applications with keyword: Preserved activity
Immobilized catalyst recycling using a SpinChem® rotating bed reactor (RBR) and a Mettler-Toledo EasyMax™ 102 Advanced synthesis workstation. The process proved very time efficient as no filtration steps were needed between cycles, or for the samples extracted for analysis during each run. Washing of the resin between runs was fast, simple and robust, without running the risk of material loss.
Conditions: A SpinChem® S2 RBR containing Novozyme 435 (1 g), was rotated at 500 rpm in a preheated (30 °C) substrate solution containing 2-Ethyl-1-hexanol (5.21 g), Vinyl acetate (3.44 mL) and heptane (110 mL). The reaction was repeated for seven cycles, and samples for each run were taken after 0, 10, 20, 30 and 60 min. Analysis of 2-Ethylhexyl acetate product was done suing GC-FID after 1:9 dilution in heptane containing internal standard (tetradecane, 50 mmol). Between cycles, the resin was washed by spinning the RBR in heptane for 1 min.
Poster on study of catalyst recycling during esterification and transesterification reactions with immobilized lipases in rotating bed reactors. Data from several laboratories showed that no attrition or grinding occurred and that no filtration was necessary between reaction cycles. The production capacity was estimated to 50 kilograms per gram of catalyst thanks to the high catalyst stability.
Conditions: This study comprised several different laboratories, immobilized enzymes, and conditions for performing esterification and transesterification reactions using a SpinChem® rotating bed reactor (RBR). The details of every reaction are displayed in connection to each figure on the poster. This poster was displayed at Biocat2016 - the 8th international congress on biocatalysis, at Hamburg University of Technology, Germany, August 28th to September 1st, 2016.
Brochure with SpinChem® rotating bed reactors (RBR) – applications, products and technology. Learn from examples how to increase speed and convenience for heterogeneous reactions in laboratory development and production scale. Read about the capabilities and handling benefits with pre-packed cartridges.
Learn how SpinChem rotating bed reactors (RBR) can eliminate poor mass transfer in heterogeneous reactions during chemical synthesis and biotransformations. Preserve activity and facilitate recycling of solid phases with the RBR. This brochure shows technology and applications.