Results are quite amazing; significantly improved reaction rate, very easy recycling and bullet-proof stability of our enzyme.

– Dr. Michiel van Vliet, R&D Manager, ChiralVision, The Netherlands


Highlighted applications

Application 1008

Accelerated video showing the enhanced adsorption rates of methylene blue onto activated carbon using a rotating bed reactor (RBR) compared to a stirred tank reactor (STR). The RBR decolourized the solution almost twice as fast, did not create any visible fines and required no filtration.

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    Conditions: Adsorption of methylene blue (100 mg) onto activated carbon (40 mL, 12-40 mesh) placed either in a SpinChem® S311 rotating bed reactor (RBR) or stirred free in solution agitated by a 5 cm impeller, both operated at 800 rpm within a SpinChem® V311 flower-baffled reaction vessel containing 1000 mL water at room temperature. The video is shown at 12x the normal speed. The solution was decolourized after 5 minutes with the RBR, versus close to 10 minutes with the stirred tank reactor (STR). Samples from the RBR set-up required no filtration, but from the STR all samples required filtration through a 45 µm syringe filter for analysis.

Application 1019

Poster on study of catalyst recycling during esterification and transesterification reactions with immobilized lipases in rotating bed reactors. Data from several laboratories showed that no attrition or grinding occurred and that no filtration was necessary between reaction cycles. The production capacity was estimated to 50 kilograms per gram of catalyst thanks to the high catalyst stability.

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    Conditions: This study comprised several different laboratories, immobilized enzymes, and conditions for performing esterification and transesterification reactions using a SpinChem® rotating bed reactor (RBR). The details of every reaction is displayed in connection to each figure on the poster. This poster was displayed at biocat2016 - the 8th international congress on biocatalysis, at Hamburg University of Technology, Germany, August 28th to September 1st, 2016.

Application 1003

Illustrative video showing how a phenolic colourant is deprotonated and extracted from an organic to an aqueous solvent. Using SpinChem® RBR in a flower-baffled reaction vessel created fine emulsion droplets resulting in effective phase-transfer between the two liquids and the solid phase.

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    Conditions: Red 2,6-dichloroindophenol (about 3 mg) in dichloromethane (70 mL) with water (70 mL) converted to its blue phenolate anion using Purolite A500P (25 mL) in OH form (created by treating Cl form with NaOH) packed into a SpinChem® RBR S221 rotating at 500 rpm in a SpinChem® V211 flower-baffled reaction vessel.

Application 1022

Convenient transfer hydrogenation catalyzed by palladium-containing beads was performed using a SpinChem® rotating bed reactor (RBR). The set-up resulted in high product conversions throughout more than 10 consecutive batches without any need for filtration to recycle the catalyst.

Application brochure

Brochure with SpinChem® rotating bed reactors (RBR) – applications, products and technology. Learn from examples how to increase speed and convenience for heterogeneous reactions in laboratory development and production scale. Read about the capabilities and handling benefits with pre-packed cartridges.

Application collection

Scientific literature