Jochen Wachtmeister and Dörte Rother
Curr. Opin. Biotechnol., 2016, 42, pp. 169-177.
“Recent advances in biocatalysis have strongly boosted its recognition as a valuable addition to traditional chemical synthesis routes. As for any catalytic process, catalyst's costs and stabilities are of highest relevance for the economic application in chemical manufacturing. Employing biocatalysts as whole cells circumvents the need of cell lysis and enzyme purification and hence strongly cuts on cost. At the same time, residual cell wall components can shield the entrapped enzyme from potentially harmful surroundings and aid to enable applications far from natural enzymatic environments. Further advantages are the close proximity of reactants and catalysts as well as the inherent presence of expensive cofactors. Here, we review and comment on benefits and recent advances in whole cell biocatalysis.”
Highlights:
Topics Biocatalysis, Scientific Literature, Reactor Engineering, Downstream Processing
Industries Pharmaceuticals and Cosmetics , Food and Beverage
Products SpinChem® RBR S2, SpinChem® RBR S3, SpinChem® Vessel V2
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