Scientific Literature

Application L1701

A novel hierarchically structured siliceous packing to boost the performance of rotating bed enzymatic reactors

Katarzyna Szymańska, Klaudia Odrozek, Aurelia Zniszczoł, Wojciech Pudło, and Andrzej B. Jarzębski Chem. Eng. J., 2017, 315, pp. 18-24.

Application L1801

Advanced oxidation process for the removal of ibuprofen from aqueous solution: A non-catalytic and catalytic ozonation study in a semi-batch reactor

Soudabeh Saeid, Pasi Tolvanen, Narendra Kumar, Kari Eränen, Janne Peltonen, Markus Peurla, Jyri-Pekka Mikkola, Andreas Franz, and Tapio Salmi Appl. Catal. B, 2018, 230, pp. 77-90.

Application L1704

Biocatalysis engineering: the big picture

Roger A. Sheldon and Pedro C. Pereira Chem. Soc. Rev., 2017, 46(10), pp. 2678-2691.

Application L1604

Catalytic hydrogenation of d-xylose over Ru decorated carbon foam catalyst in a SpinChem® rotating bed reactor

Tung Ngoc Pham, Ajaikumar Samikannu, Anne-Riikka Rautio, Koppany L. Juhasz, Zoltan Konya, Johan Wärnå, Krisztian Kordas, and Jyri-Pekka Mikkola Top. Catal., 2016, 59, pp. 1165-1177.

Application L1702

CFD modeling of flow and ion exchange kinetics in a rotating bed reactor system

Hilde Larsson, Patrick Alexander Schjøtt Andersen, Emil Byström, Krist V. Gernaey, and Ulrich Krühne Ind. Eng. Chem. Res., 2017, 56, 14, pp. 3853-3865.

Application L1601

Deconstruction of Nordic hardwood in switchable ionic liquids and acylation of the dissolved cellulose

Valerie Eta and Jyri-Pekka Mikkola Carbohydr. Polym., 2016, 136, pp. 459-465.

Application L2204

Design of a green chemoenzymatic cascade for scalable synthesis of bio-based styrene alternatives

Philipp Petermeier, Jan Philipp Bittner, Simon Müller, Emil Byström, and Selin Kara Green Chemistry, 2022, 24(18), pp. 6889-6899.

Application L1301

Efficient biocatalysis with immobilized enzymes or encapsulated whole cell microorganism by using the SpinChem reactor system

Hendrik Mallin, Jan Muschiol, Emil Byström, and Uwe T. Bornscheuer ChemCatChem, 2013, 5, pp. 3529-3532.

Application L1401

Enhanced mass transfer upon switchable ionic liquid mediated wood fractionation

Valerie Eta, Ikenna Anugwom, Pasi Virtanen, P. Mäki-Arvelaa, and Jyri-Pekka Mikkola Ind. Crops Prod., 2014, 55, pp. 109-115.

Application L1802

Epoxidation of fatty acids and vegetable oils assisted by microwaves catalyzed by a cation exchange resin

Adriana Freites Aguilera, Pasi Tolvanen, Shuyana Heredia, Marta González Muñoz, Tina Samson, Adrien Oger, Antoine Verove, Kari Eränen, Sebastien Leveneur, Jyri-Pekka Mikkola, and Tapio Salmi Ind. Eng. Chem. Res., 2018, 57(11), pp. 3876-3886.

Application L1605

Fibre stress-strain response of high-temperature chemi-thermomechanical pulp treated with switchable ionic liquids

Ran Duan, Bo S. Westerlind, Magnus Norgren, Ikenna Anugwom, Pasi Virtanen, and Jyri-Pekka Mikkola BioRes., 2016, 11(4), pp. 8570-8588.

Application L2213

Impact of critical parameters influencing enzymatic production of structured lipids using response surface methodology with water activity control

Ariana Causevic, Eimantas Gladkauskas, Kim Olofsson, Patrick Adlercreutz, and Carl Grey Biochem. Eng. J., 2022, 187, 108610.

Application L1603

In quest for the optimal delignification of lignocellulosic biomass using hydrated, SO2 switched DBU MEASIL switchable ionic liquid

Ikenna Anugwoma, Luis Rujana, Johan Wärnå, Mattias Hedenström, and Jyri-Pekka Mikkola Chem. Eng. J., 2016, 297, pp. 256-264.

Application L1903

L-Asparaginase production in rotating bed reactor from Rhizopus microsporus IBBL-2 using immobilized Ca-alginate beads

Anup Ashok and Santhosh Kumar Devarai 3 Biotech, 2019, 9(9), 349.

Application L1402

Lipase catalyzed regioselective lactamization as a key step in the synthesis of N-Boc (2R)-1,4-oxazepane-2-carboxylic acid

Carl-Johan Aurell, Staffan Karlsson, Fritiof Pontén, and Søren M. Andersen Org. Process Res. Dev., 2014, 18(9), pp. 1116-1119.

Application L1602

Modularized biocatalysis: Immobilization of whole cells for preparative applications in microaqueous organic solvents

Jochen Wachtmeister, Philip Mennicken, Andreas Hunold, and Dörte Rother ChemCatChem, 2016, 8, pp. 607-614.

Application L2117

Multi‐enzyme cascade reaction in a miniplant two‐phase‐system: Model validation and mathematical optimization

Jens Johannsen, Francesca Meyer, Claudia Engelmann, Andreas Liese, Georg Fieg, Paul Bubenheim, and Thomas Waluga AIChE J., 2021, 67(4), e17158.

Application L2102

New frontiers in enzyme immobilisation: Robust biocatalysts for a circular bio-based economy

Roger A. Sheldon, Alessandra Basso, and Dean Brady Chem. Soc. Rev., 2021, 50(10), pp. 5850-5862.

Application L2110

Process design of a continuous biotransformation with in situ product removal by cloud point extraction

Oliver Fellechner and Irina Smirnova Can. J. Chem. Eng., 2021, 99, pp. 1035-1049.

Application L2112

Production of hydroxytyrosol rich extract from Olea europaea leaf with enhanced biological activity using immobilized enzyme reactors

Alexandra V. Chatzikonstantinou, Αrchontoula Giannakopoulou, Stamatia Spyrou, Yannis V. Simos, Vassiliki G. Kontogianni, Dimitrios Peschos, Petros Katapodis, Angeliki C. Polydera, and Haralambos Stamatis Environ. Sci. Pollut. Res., 2022, 29, pp. 29624-29637.

Application L2115

Production of recombinant choline oxidase and its application in betaine production

S. Lokesha, Y. S. Ravi Kumar, P. S. Sujan Ganapathy, Prashant Gaur, and H. M. Arjun 3 Biotech, 2021, 11, 410.

Application L1901

Progress on the pre-treatment of lignocellulosic biomass employing ionic liquids

Pobitra Halder, Sazal Kundu, Savankumar Patel, Adi Setiawan, Rob Atkin, Rajarathinam Parthasarthy, Jorge Paz-Ferreiro, Aravind Surapaneni, and Kalpit Shah Renewable Sustainable Energy Rev., 2019, 105, pp. 268-292.

Application L2119

Pseudomonas taiwanensis biofilms for continuous conversion of cyclohexanone in drip flow and rotating bed reactors

Ingeborg Heuschkel, Selina Hanisch, Daniel C. Volke, Erik Löfgren, Anna Hoschek, Pablo I. Nikel, Rohan Karande, and Katja Bühler Eng. Life Sci., 2021, 21(3-4), pp. 258-269.

Application L1703

Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy

M. Aßmann, A. Stöbener, C. Mügge, S. K. Gaßmeyer, L. Hilterhaus, R. Kourist, A. Liese, and S. Kara React. Chem. Eng., 2017, 2(4), pp. 531-540.

Application L1606

Recent advances in whole cell biocatalysis techniques bridging from investigative to industrial scale

Jochen Wachtmeister and Dörte Rother Curr. Opin. Biotechnol., 2016, 42, pp. 169-177.

Application L1705

Role of biocatalysis in sustainable chemistry

Roger A. Sheldon and John M. Woodley Chem. Rev., 2018, 118(2), pp. 801-838.

Application L2005

Solvent and rotating bed reactor extraction with one- and two-phase solvents applied to bilberries (Vaccinium myrtillus) for isolating valuable antioxidants

Josefina Nyström, Ulla-Britt Östman, Torgny Mossing, Leif Hed, and Paul Geladi Food Anal. Methods, 2020, 13, pp. 933-941.

Application L2001

Using SpinChem rotating bed reactor technology for immobilized enzymatic reactions: A case study

Subhash Pithani, Staffan Karlsson, Hans Emtenäs, and Christopher T. Öberg Org. Process Res. Dev., 2019, 23(9), pp. 1926-1931.

Application L1706

Whole-cell cascade biotransformations for one-pot multistep organic synthesis

Shuke Wu and Zhi Li ChemCatChem, 2018, 10(10), pp. 2164-2178.

Application L2202

Asymmetric hydrogenation of C = C bonds in a SpinChem reactor by immobilized old yellow enzyme and glucose dehydrogenase

Teng Ma, Weixi Kong, Yunting Liu, Hao Zhao, Yaping Ouyang, Jing Gao, Liya Zhou, and Yanjun Jiang Appl. Biochem. Biotechnol., 2022, 194, pp. 4999–5016.

Application L2207

Lipase catalyzed green epoxidation of oleic acid using ultrasound as a process intensification method

Adriana Freites Aguilera, Pontus Lindroos, Jani Rahkila, Mark Martinez Klimov, Pasi Tolvanen, and Tapio Salmi Chem. Eng. Process. Process Intensif., 2022, 174, 108882.

Application L2212

Epoxidation of tall oil fatty acids and tall oil fatty acids methyl esters using the SpinChem® rotating bed reactor

Krzysztof Polaczek, Eliza Kaulina, Ralfs Pomilovskis, Anda Fridrihsone, and Mikelis Kirpluks J. Polym. Environ., 2022, 30, pp. 4774–4786.

Application L2203

Peroxygenase-driven ethylbenzene hydroxylation in a rotating bed reactor

Markus Hobisch, Piera De Santis, Simona Serban, Alessandra Basso, Emil Byström, and Selin Kara Org. Process Res. Dev., 2022, 26(9), pp. 2761-2765.

Application L2301

Comparison of four immobilization methods for different transaminases

Tobias Heinks, Nicolai Montua, Michelle Teune, Jan Liedtke, Matthias Höhne, Uwe T. Bornscheuer, and Gabriele Fischer von Mollard Catalysts, 2023, 13(2), 300.

Application L2302

Fatty acid epoxidation on enzymes: Experimental study and modeling of batch and semibatch operation

Wilhelm Wikström, Adriana Freites Aguilera, Pasi Tolvanen, Robert Lassfolk, Ananias Medina, Kari Eränen, and Tapio Salmi Ind. Eng. Chem. Res., 2023, 62(23), pp. 9169-9187.

Application L2303

Amination of a green solvent via immobilized biocatalysis for the synthesis of Nemtabrutinib

Christopher K. Prier, Karla Camacho Soto, Jacob H. Forstater, Nadine Kuhl, Jeffrey T. Kuethe, Wai Ling Cheung-Lee, Michael J. Di Maso, Claire M. Eberle, Shane T. Grosser, Hsing-I Ho, Erik Hoyt, Anne Maguire, Kevin M. Maloney, Amanda Makarewicz, Jonathan P. McMullen, Jeffrey C. Moore, Grant S. Murphy, Karthik Narsimhan, Weilan Pan, Nelo R. Rivera, Anumita Saha-Shah, David A. Thaisrivongs, Deeptak Verma, Adeya Wyatt, and Daniel Zewge ACS Catal., 2023, 13(12), pp. 7707-7714.

Application L2120

Rotating bed reactor packed with heterofunctional structured silica-supported lipase. Developing an effective system for the organic solvent and aqueous phase reactions

Daria Kowalczykiewicz, Katarzyna Szymańska, Danuta Gillner, and Andrzej B. Jarzębsk Microporous Mesoporous Mater., 2021, 312, 110789.

Application L2116

Prilezhaev epoxidation of oleic acid in the presence and absence of ultrasound irradiation

Adriana Freites Aguilera, Roosa Hämäläinen, Kari Eränen, Pasi Tolvanen, and Tapio Salmi J. Chem. Technol. Biotechnol., 2021, 96(7), pp. 1874-1881.

Application L2002

Determination of kinetics and equilibria of heterogeneously catalyzed gas-phase reactions in gradientless autoclave reactors by using the total pressure method: Methanol synthesis

Tapio Salmi, Kari Eränen, Pasi Tolvanen, J.-P. Mikkola, and Vincenzo Russo Chem. Eng. Sci., 2020, 215, 115393.

Application L2004

Advanced oxidation process for degradation of carbamazepine from aqueous solution: influence of metal modified microporous, mesoporous catalysts on the ozonation process

Soudabeh Saeid, Matilda Kråkström, Pasi Tolvanen, Narendra Kumar, Kari Eränen, Jyri-Pekka Mikkola, Leif Kronberg, Patrik Eklund, Markus Peurla, Atte Aho, Andrey Shchukarev and Tapio Salmi Catalysts, 2020, 10(1), 90.

Application L2003

Pharmaceutical industry perspectives on flow chemocatalysis and biocatalysis

Laura Leemans Martin, Theo Peschke, Francesco Venturoni, and Serena Mostarda Curr. Opin. Green Sustainable Chem., 2020, 25, 100350.

Application L2006

Epoxidation of tall oil catalyzed by an ion exchange resin under conventional heating and microwave irradiation

Adriana Freites Aguilera, Jani Rahkila, Jarl Hemming, Maristiina Nurmi, Gaetan Torres, Théophile Razat, Pasi Tolvanen, Kari Eränen, Sébastien Leveneur, and Tapio Salmi Ind. Eng. Chem. Res., 2020, 59(22), pp. 10397-10406.

Application L2104

Compartmentalization in biocatalysis

Robert Kourist and Javier González‐Sabín In: Biocatalysis for Practitioners: Techniques, Reactions and Applications

Application L2111

Streamlining design, engineering, and applications of enzymes for sustainable biocatalysis

Roger A. Sheldon and Dean Brady ACS Sustainable Chem. Eng., 2021, 9(24), pp. 8032–8052.

Application L2114

Practical multienzymatic transformations: Combining enzymes for the one‐pot synthesis of organic molecules in a straightforward manner

Jesús Albarrán‐Velo, Sergio González‐Granda, Marina López‐Agudo, and Vicente Gotor‐Fernández In: Biocatalysis for Practitioners: Techniques, Reactions and Applications

Application L2106

Interaction of intrinsic kinetics, catalyst durability and internal mass transfer in the oxidation of sugar mixtures on gold nanoparticle extrudates

Maria Herrero Manzano, Kari Eränen, Kari, Adriana Freites Aguilera, Johan Wärnå, Sebastian Franz, Markus Peurla, Juan García Serna, Dmitry Murzin, and Tapio Salmi Ind. Eng. Chem. Res., 2021, 60(18), pp. 6483-6500.

Application L2008

Probing batch and continuous flow reactions in organic solvents: Granulicella tundricola hydroxynitrile lyase (GtHNL)

José Coloma, Yann Guiavarc'h, Peter-Leon Hagedoorn, and Ulf Hanefeld Catal. Sci. Technol., 2020, 10(11), pp. 3613-3621.

Application L2201

A critical review on ibuprofen removal from synthetic waters, natural waters, and real wastewaters by advanced oxidation processes

Enric Brillas Chemosphere, 2022, 286, Part 3, 131849.

Application L2009

Synthesis and characterization of metal modified catalysts for decomposition of ibuprofen from aqueous solutions

Soudabeh Saeid, Matilda Kråkström, Pasi Tolvanen, Narendra Kumar, Kari Eränen, Markus Peurla, Jyri-Pekka Mikkola, Laurent Maël, Leif Kronberg, Patrik Eklund, and Tapio Salmi Catalysts, 2020, 10(7), 786.

Application L2304

Boosting the catalytic performance of a marine yeast in a SpinChem® reactor for the synthesis of perillyl alcohol

Silvia Donzella, Concetta Compagno, Francesco Molinari, Francesca Paradisi, and Martina Letizia React. Chem. Eng., 2023, 8(12), pp. 2963-2966.

Application L2305

Enzymatic synthesis of ascorbyl palmitate in a rotating bed reactor

Jessica Holtheuer, Luigi Tavernini, Claudia Bernal, Oscar Romero, Carminna Ottone, and Lorena Wilson Molecules, 2023, 28(2), 644.

Application L2306

Selective peroxygenase-catalysed oxidation of toluene derivatives to benzaldehydes

Yutong Wang, Niklas Teetz, Dirk Holtmann, Miguel Alcalde, Jacob M. A. van Hengst, Xiaoxiao Liu, Mengfan Wang, Wei Qi, Wuyuan Zhang, and Frank Hollmann ChemCatChem, 2023, 15(13), e202300645.

Application L2208

Process intensification in oxidative biocatalysis

Guillem Vernet, Markus Hobisch, and Selin Kara Curr. Opin. Green Sustainable Chem., 2022, 38, 100692.

Application L2209

Chemical wastes in the peptide synthesis process and ways to reduce them

Mahan Haji Abbasi Somehsaraie, Vaezeh Fathi Vavsari, Mohammad Kamangar, and Saeed Balalaie Iran. J. Pharm. Res., 2022, 21(1), e123879.

Application L2309

Screening, synthesis optimization, and scaling-up of phytopathogen antifungals derived from natural hydroxycinnamic acids

Doddy Denise Ojeda-Hernández, Ana Daniela Vega-Rodríguez, Ali Asaff-Torres, and Juan Carlos Mateos-Díaz 3 Biotech, 2023, 13, 13.

Application L2310

Large scale production of vanillin using an eugenol oxidase from Nocardioides sp. YR527

Daniel Eggerichs, Kathrin Zilske, and Dirk Tischler Mol. Catal., 2023, 546, 113277.

Application L2311

New enzymatic reactor designs: From enzymatic batch to 3D microreactors and monoliths

Kim Shortall, Katarzyna Szymańska, Cristina Carucci, Tewfik Soulimane, and Edmond Magner In: Biocatalyst Immobilization, Foundations and Applications, 2022