Application L2119

Pseudomonas taiwanensis biofilms for continuous conversion of cyclohexanone in drip flow and rotating bed reactors

This article involves the use of a rotating bed reactor for a biocatalytic process involving biofilms.

The biofilm of Pseudomonas taiwanensis, with a genetically introduced Baeyer-Villiger monooxygenase (BVMO), was grown directly on 3D-printed polyamide inserts installed in the RBR S3. The biofilm, immobilized on the cartridges, was then used to catalyze the conversion of cyclohexanone. The authors comment that the work opens up the possibility to use biofilms in rotating bed reactors for synthesis via biocatalysis.


Authors: Heuschkel, Ingeborg; Hanisch, Selina; Volke, Daniel C; Löfgren, Erik; Hoschek, Anna; Nikel, Pablo I; Karande, Rohan; Bühler, Katja Publication date: March 2021 DOI: 10.1002/elsc.202000072

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