Application 1021
Demonstration of loading, reaction and unloading in a production scale rotating bed reactor

Video showing how a SpinChem® rotating bed reactor (RBR) for use in 20-300 L vessels was charged with solid particles, used for pH neutralization, drained from reaction liquid and finally emptied from solid phase without opening the RBR. This procedure illustrates one approach to using RBR in production scale equipment without opening the reaction vessel.  Keywords: Easy handling, Ion exchange, Seamless scaleup, Technology

Application 1013
Flow rate determination in a connected system with rotating bed reactors

Short video of a coloured dye front moving in a transparent liquid through a pipe connecting an external rotating bed reactor to a larger vessel. The total convective flow rate was calculated to 440 L/h based on linear progression of the dye and assuming steady state turbulent conditions at Reynolds number 7900.  Keywords: Continuous flow, Seamless scaleup, Technology

Application 1029
Effects of channelling on flow rates through rotating bed reactors and fixed bed reactors

The performance and robustness of the SpinChem® rotating bed reactor (RBR) technology was examined and compared to a fixed bed reactor (FBR) using ANSYS Fluent. By means of flow simulations through loosely packed beds, the RBR was found to be extremely robust with respect to the level of packing of the solid phase within, while the FBR was negatively affected by channelling.  Keywords: Easy handling, Simulation, Technology

Application 1016
In situ filling and emptying of rotating bed reactors

Video showing how a SpinChem® rotating bed reactor (RBR) was charged with solid particles, followed by draining and replacing the reaction liquid without escape of solids. Lastly, the solid phase was removed without opening the RBR. This procedure illustrates a concept for automatic handling of solid phases in production scale equipment without opening the reaction vessel.  Keywords: Easy handling, Seamless scaleup, Technology

Brochure
Mass transfer revolutionized

Learn how SpinChem rotating bed reactors (RBR) can eliminate poor mass transfer in heterogeneous reactions during chemical synthesis and biotransformations. Preserve activity and facilitate recycling of solid phases with the RBR. This brochure shows technology and applications.  Keywords: Biotransformation, Brochure, Fast reaction, Immobilized enzymes, Molecular sieve, Preserved activity, Simple cleanup, Synthesis, Technology

Application 1032
Rotating bed reactor for immobilized enzymatic reactions

Poster on a case study of applying the rotating bed reactor for the lipase-mediated stereoselective acetylation of a racemate amine as a model reaction for the manufacturing of pharmaceutical building blocks. The results showed that enzyme recycling and synthesis scale up was easy to achieve with preserved yield, enantioselectivity and catalytic activity.   Keywords: Biotransformation, Easy handling, Immobilized enzymes, Quick recycling, Seamless scaleup

Application 1025
Rotating bed reactor setup for in situ formation, loading and handling of alginate beads and whole cell encapsulation

Video showing the formation of alginate beads under conditions mimicking whole cell encapsulation. The use of a SpinChem® rotating bed reactor (RBR) allowed easy collection, maturing and washing of the alginate beads. With the RBR setup, it was possible to immediately continue with filling of the reaction substrate into the same vessel, thus reducing the number of handling steps and facilitating bead recycling. The beads showed no signs of physical wear after use in the RBR.   Keywords: Alginate, Biotransformation, Easy handling, One-pot multistep, Technology

Application 1010
Rotating bed reactors completely avoid grinding of molecular sieves

Photos showing how grinding caused by stirring of molecular sieves can be completely avoided by using a rotating bed reactor (RBR). Molecular sieves contained in a RBR for a 200 mL vessel can theoretically hold 0.23 moles of water. This allows synthesis of product in the range of 100 gram by ester condensation or drying of 25 litres of analytical grade organic solvent. Keywords: Easy handling, Molecular sieve, Purification, Simple cleanup, Synthesis, Technology, Water

Application 1020
Simulation of flow patterns around a rotating bed reactor in a flower baffled reaction vessel

Computational fluid dynamics simulations is an important tool in the optimization of geometries during development of SpinChem® rotating bed reactor (RBR) products. The image shows velocity vectors in a cross section of the flow around a SpinChem® RBR, in a flower baffled reaction vessel, simulated using ANSYS Fluent software under typical laboratory conditions.  Keywords: Behind the scenes, Simulation, Technology

Application 1009
Simultaneous extraction of two dyes selectively onto different resins

Video illustrating how a mixture of red and blue dyes with different chemical properties can be selectively extracted onto different adsorbents within the same run using a rotating bed reactor (RBR). The dyes were separated based on ionic and hydrophobic interactions, respectively.  Keywords: Cleantech, Decolouration, Extraction, Ion exchange, One-pot multistep, Organic molecules, Polymeric resin, Technology

Application 9003
Simultaneous Selective Decolouration – Illustrating a Concept for Cascade Reactions

Two dyes were selectively extracted onto different adsorbents within the same run using a SpinChem® rotating bed reactor (RBR) and an EasyMax™ 102 Advanced synthesis workstation. This experiment illustrates performing cascade reaction for one-pot multi-step synthesis.  Keywords: Cleantech, Decolouration, Extraction, Ion exchange, One-pot multistep, Organic molecules, Polymeric resin, Technology

MagRBR and stirrer

Instruction video for the MagRBR and stirrer 

Assembly guide for Rotating Bed Reactor S2

Assembly guide for Rotating Bed Reactor S2

SpinChem RBR S3 and S3+ Assembly Guide

Assembly guide for SpinChem RBR S3 and S3+

SpinChem RBR S4, S5 and S14 Assembly Guide

SpinChem RBR S4, S5 and S14 Assembly Guide

SpinChem Assembly Guide: V2 Reaction Vessel

Assembly Guide: V2 Reaction Vessel

SpinChem Assembly Guide: Laboratory Stand

SpinChem Assembly Guide: Laboratory Stand

SpinChem RBR Tips ‘n’ Tricks

SpinChem RBR Tips ‘n’ Tricks

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