Poster on a case study of applying the rotating bed reactor for the lipase-mediated stereoselective acetylation of a racemate amine as a model reaction for the manufacturing of pharmaceutical building blocks. The results showed that enzyme recycling and synthesis scale up was easy to achieve with preserved yield, enantioselectivity and catalytic activity.
Industries Pharmaceutical and Cosmetics , Flavour and Fragrances, Food and Beverage
Topics Biocatalysis, Reactor Engineering, Reaction screening, Process development, Downstream Processing, Support
Products SpinChem® RBR S2, SpinChem® Vessel V2
Details
Conditions: This poster contains data from several reactions with immobilized enzymes performed at different conditions. The details of each reaction are displayed under each figure in the poster. This poster was presented at BioTrans2019 - the 14th international symposium on biocatalysis and biotransformations, in Groningen, Netherlands, the 7th to 11th of July, 2019.
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